By D.R. Welch

This quantity is the 1st try to summarize present wisdom in regards to the underlying molecular and biochemical mechanisms controlling the metastatic phenotype. whereas all earlier authors tried to place their findings right into a context for translation to the medical scenario, the cutting-edge doesn't totally permit this as the box of metastasis is comparatively new. still, the contents of this quantity may be of use to individuals of the melanoma examine neighborhood and clinicians attracted to constructing and enforcing novel types of remedy for melanoma.

Show description

Read Online or Download Cancer Metastasis -- Related Genes (CANCER METASTASIS -- BIOLOGY AND TREATMENT Volume 3) (Cancer Metastasis - Biology and Treatment) PDF

Best biophysics books

Molekulare Pharmakologie und Toxikologie: Biologische Grundlagen von Arzneimitteln und Giften

Wie wirkt ein Medikament oder ein present in der Zelle? Thomas Efferth spannt einen Bogen von den allgemeinen Grundlagen der Pharmakologie und Toxikologie zu den molekularen Wirkmechanismen der wichtigsten Medikamente und Gifte. Aktuelle Themen wie Gentherapie, Immuntherapie und Stammzelltherapie behandelt er ebenso wie Pharmakogenetik und –genomik oder systembiologische Ans?

Additional info for Cancer Metastasis -- Related Genes (CANCER METASTASIS -- BIOLOGY AND TREATMENT Volume 3) (Cancer Metastasis - Biology and Treatment)

Example text

An expressed-sequence-tag database of the human prostate: sequence analysis of 1168 cDNA clones. Genomics 1998; 47:12-25. 146. Hawkins V, Doll D, Bumgarner R, et al. PEDB: the Prostate Expression Database. Nucleic Acids Res 1999; 27:204-8. 147. Bissell MJ, Weaver VM, Lelievre SA, Wang F, Petersen OW, Schmeichel KL. Tissue structure, nuclear organization, and gene expression in normal and malignant breast. Cancer Res 1999; 59:1757-1763s; discussion 1763s-1764s. 148. Boudreau N, Bissell MJ. Extracellular matrix signaling: integration of form and function in normal and malignant cells.

Critical determinants of melanoma metastasis. J Investig Dermatol Symp Proc 1996; 1:203-8. 45. Day ML, Zhao X, Vallorosi CJ, et al. E-cadherin mediates aggregation-dependent survival of prostate and mammary epithelial cells through the retinoblastoma cell cycle control pathway. J Biol Chem 1999; 274:9656-64. 46. Guilford P. E-cadherin downregulation in cancer: fuel on the fire? Mol Med Today 1999; 5:172-7. 47. Giancotti FG, Ruoslahti E. Integrin signaling. Science 1999; 285:1028-32. 48. Arbiser JL, Moses MA, Fernandez CA, et al.

70. Berube NG, Speevak MD, Chevrette M. Suppression of tumorigenicity of human prostate cancer cells by introduction of human chromosome del(12)(q13). Cancer Res 1994; 54:3077-81. 71. Pienta KJ, Coffey DS. Nuclear-cytoskeletal interactions: evidence for physical connections between the nucleus and cell periphery and their alteration by transformation. J Cell Biochem 1992; 49:357-65. 72. Miele ME, Robertson G, Lee JH, et al. Metastasis suppressed, but tumorigenicity and local invasiveness unaffected, in the human melanoma cell line MelJuSo after introduction of human chromosomes 1 or 6.

Download PDF sample

Rated 4.31 of 5 – based on 41 votes