By Richard Appleton; D F Smith

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40). Variant CJD has been recognized since the mid1990s, mainly in the UK, and is now known to result from ingestion of food products infected with bovine spongiform encephalopathy (BSE). Most commonly variant CJD presents in younger patients than in the sporadic form of the disease and frequently has a neuropsychiatric presentation, with anxiety, depression and widespread sensory symptoms being com- mon early features. Seizures may occur, and can mimic myoclonic epilepsy. There is an inevitable progressive ataxia and dementia with death usually within 2 years of onset.

7. Commission on classification and Terminology of the International League Against Epilepsy. Proposal for classification of epilepsies and epileptic syndromes. Epilepsia 1989; 30: 389–99 Stephenson JBP. Fits and Faints. London: MacKeith Press, 1990: 103 Chadwick D. Paroxysmal disorders. In Chadwick D, Cartlidge NEF, Bates D, eds. Medical Neurology. Edinburgh: Churchill Livingstone, 1989: 152–85 Engel J Jr. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy: report of the ILAE Task Force on Classification and Terminology.

5–2 Hz on a diffusely slow background for the child’s age. 11 Central nervous system disease causing seizures and epilepsy. 12 Systemic disturbances causing seizures Fever Hypoxia Hypoglycemia Electrolyte imbalance Renal failure Hepatic failure Respiratory failure Drugs Drug withdrawal Toxins Pyridoxine deficiency Porphyria Inborn errors of metabolism meningitis, encephalitis abscess, syphilis Trauma diffuse brain injury, hematoma (extradural, subdural, intracerebral) depressed skull fracture Tumor glioma, meningioma secondary carcinoma, etc.

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